ABSTRACT
Objective To investigate the effect and mechanism of extracorporeal shock wave therapy(ES-WT)on typeⅢB chronic prostatitis. Methods A total of 90 patients with CP/CPPS in our department from June 2015 to February 2017 were collected and randomly divided into experimental and control groups ,each with 45 cases. The control group was treated with hyperthermia. The experimental group was treated with ESWT. Both two groups were treated for 2 courses. Following parameters were collected after two groups were treated for 2 courses:chronic prostatitis symptom score (NIH-CPSI),the International Prostate Symptom Score (IPSS),the content changes in prostate fluid IL-8,TNF-alpha,IL-1 beta,lecithin and the content change of urine IL-8,TNF-alpha, IL-6. Results After 2 courses of treatment,compared with the control group,the overall efficiency of experimen-tal group was increased(91.11%vs. 66.67%,P<0.05). NIH-CPSI(13.12 ± 1.71 vs. 18.16 ± 1.33,P<0.05)and IPSS(8.03 ± 1.78 vs. 13.04 ± 1.89,P<0.05)scores were decreased. In terms of inflammatory,compared with the control group,in the experimental group,the content of lecithin body was significantly increased. The levels of inflammatory factors IL-8、TNF-α、IL-1βwere significantly decreased in the prostatic fluid and urine. Conclusion ESWT is safe and effective in the treatment of type ⅢB prostatitis ,which may be caused by reducing the local inflammatory response in the prostate.
ABSTRACT
Objective To investigate the effect and mechanism of extracorporeal shock wave therapy(ES-WT)on typeⅢB chronic prostatitis. Methods A total of 90 patients with CP/CPPS in our department from June 2015 to February 2017 were collected and randomly divided into experimental and control groups ,each with 45 cases. The control group was treated with hyperthermia. The experimental group was treated with ESWT. Both two groups were treated for 2 courses. Following parameters were collected after two groups were treated for 2 courses:chronic prostatitis symptom score (NIH-CPSI),the International Prostate Symptom Score (IPSS),the content changes in prostate fluid IL-8,TNF-alpha,IL-1 beta,lecithin and the content change of urine IL-8,TNF-alpha, IL-6. Results After 2 courses of treatment,compared with the control group,the overall efficiency of experimen-tal group was increased(91.11%vs. 66.67%,P<0.05). NIH-CPSI(13.12 ± 1.71 vs. 18.16 ± 1.33,P<0.05)and IPSS(8.03 ± 1.78 vs. 13.04 ± 1.89,P<0.05)scores were decreased. In terms of inflammatory,compared with the control group,in the experimental group,the content of lecithin body was significantly increased. The levels of inflammatory factors IL-8、TNF-α、IL-1βwere significantly decreased in the prostatic fluid and urine. Conclusion ESWT is safe and effective in the treatment of type ⅢB prostatitis ,which may be caused by reducing the local inflammatory response in the prostate.
ABSTRACT
Objective To investigate the improving efficacy of hospital -family bed nursing model on pa-tients with post -stroke depression.Methods 80 patients with post -stroke depression were randomly divided into two groups,40 cases in each group.In -hospital comprehensive rehabilitation intervention was applied in the control group,while comprehensive rehabilitation intervention of hospital -family bed was conducted in the observation group.Hamilton Depression Scale (HAMD)was adopted to evaluate the depressive condition before and after inter-vention.Non -conditional logistic regression analysis was applied to analyze the correlation between the patients'age, sex,scores before intervention,hospital -family bed nursing model and the improvement level of HAMD scores. Results The HAMD scores after nursing intervention in observation group and control group were significantly decreased [(control group from (29.57 ±5.69)points to (19.22 ±7.21)points,t =10.329,P =0.000;observation group from (28.60 ±4.12)points to (12.02 ±5.81)points,t =14.302,P =0.000)].After intervention,HAMD score in the observation group was significantly lower than the control group (t =0.786,P =0.000).The effective rate of the observation group was higher than the control group(97.5% vs.70.0%,χ2 =11.114,P =0.001).The results of multivariate logistic regression analysis showed scores before intervention (95%CI:0.788 -0.995,P =0.040)and hospital -family bed nursing model (95%CI:2.501 -23.309,P =0.000)were the independent factors of the reduction of HAMD score.Conclusion Rehabilitation nursing using hospital -family bed nursing model has a markedly effect on patients with post -stroke depression and it deserves the clinical expansion.